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Lysinyl Macrocyclic Hexaoxazoles: Synthesis and Selective G-Quadruplex Stabilizing Properties

Macrocyclic hexaoxazoles having one or two lysinyl side chains in which the terminal nitrogen is either a primary amine, N,N-dimethylamine, or an acetamide have been synthesized. Sodium ion has been found to be beneficial to the macrocyclization step by acting as a template around which the linear p...

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Hlavní autoři: Rzuczek, Suzanne G., Pilch, Daniel S., LaVoie, Edmond J., Rice, Joseph E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262165/
https://ncbi.nlm.nih.gov/pubmed/18248989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.12.048
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