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Lysinyl Macrocyclic Hexaoxazoles: Synthesis and Selective G-Quadruplex Stabilizing Properties
Macrocyclic hexaoxazoles having one or two lysinyl side chains in which the terminal nitrogen is either a primary amine, N,N-dimethylamine, or an acetamide have been synthesized. Sodium ion has been found to be beneficial to the macrocyclization step by acting as a template around which the linear p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262165/ https://ncbi.nlm.nih.gov/pubmed/18248989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.12.048 |
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