Llwytho...

Macrocyclic biphenyl tetraoxazoles: Synthesis, evaluation as G-quadruplex stabilizers and cytotoxic activity

A series of macrocyclic biphenyl tetraoxazoles was synthesized. The latter stages of the synthetic approach allowed for the addition of varied N-protected α-amino acids, which were subsequently deprotected and condensed to provide the desired macrocycles. Improved yields could be realized in the mac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Blankson, Gifty A., Pilch, Daniel S., Liu, Angela A., Liu, Leroy F., Rice, Joseph E., LaVoie, Edmond J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949619/
https://ncbi.nlm.nih.gov/pubmed/23787291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.05.033
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