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Targeting Human Telomeric G-Quadruplex DNA with Oxazole-Containing Macrocyclic Compounds
Oxazole-containing macrocycles, which include the natural product telomestatin, represent a promising class of anticancer agents that target G-quadruplex DNA. Two synthetic hexaoxazole-containing macrocyclic compounds (HXDV and HXLV-AC) have been characterized with regard to their cytotoxic activiti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587169/ https://ncbi.nlm.nih.gov/pubmed/18439430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2008.03.011 |
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