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A Study of the Scope and Regioselectivity of the Ruthenium-Catalyzed [3+2]-Cycloaddition of Azides with Internal Alkynes

[Figure: see text] [3+2]-Cycloadditions of alkyl azides with various unsymmetrical internal alkynes in the presence of Cp*RuCl(PPh(3))(2) as catalyst in refluxing benzene have been examined, leading to 1,4,5-trisubstituted-1,2,3-triazoles. Whereas alkyl phenyl and dialkyl acetylenes undergo cycloadd...

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Autors principals: Majireck, Max M., Weinreb, Steven M.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518321/
https://ncbi.nlm.nih.gov/pubmed/17064059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo061688m
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