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Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition

In this study, we described the synthesis of 1,4- and 1,5-disubstituted-1,2,3-triazolo-nucleosides from various alkynes with 1′-azido-2′,3′,5′-tri-O-acetylribose using either copper-catalyzed azide-alkyne cycloaddition (CuAAC) or ruthenium-catalyzed azide-alkyne cycloaddition (RuAAC), respectively....

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Detalles Bibliográficos
Publicado en:Tetrahedron
Autores principales: Pradere, Ugo, Roy, Vincent, McBrayer, Tamara R., Schinazi, Raymond F., Agrofoglio, Luigi A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315236/
https://ncbi.nlm.nih.gov/pubmed/34321698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.07.007
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