Role of Matrix Metalloproteinase-2 in Newborn Mouse Lungs under Hypoxic Conditions

Hypoxia impairs normal neonatal pulmonary artery remodeling and alveolar development. Matrix metalloproteinase-2 (MMP-2), which regulates collagen breakdown, is important during development. Our objective was to test the hypothesis that hypoxia attenuates the normal postnatal increase in MMP-2 and e...

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Main Authors: AMBALAVANAN, NAMASIVAYAM, NICOLA, TEODORA, LI, PENG, BULGER, ARLENE, MURPHY-ULLRICH, JOANNE, OPARIL, SUZANNE, CHEN, YIU-FAI
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517580/
https://ncbi.nlm.nih.gov/pubmed/18043506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31815b690d
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