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Serine Hydrolase KIAA1363: Toxicological and Structural Features with Emphasis on Organophosphate Interactions

Serine hydrolase KIAA1363 is highly expressed in invasive cancer cells and is the major protein in mouse brain diethylphosphorylated by and hydrolyzing low levels of chlorpyrifos oxon (CPO) (the activated metabolite of a major insecticide). It is also the primary CPO-hydrolyzing enzyme in spinal cor...

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Main Authors: Nomura, Daniel K., Durkin, Kathleen A., Chiang, Kyle P., Quistad, Gary B., Cravatt, Benjamin F., Casida, John E.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2512971/
https://ncbi.nlm.nih.gov/pubmed/16978018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060117m
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