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Interaction of the Serine Hydrolase KIAA1363 with Organophosphorus Agents: Evaluation of Potency and Kinetics

Oxons are bioactive metabolites of organophosphorus insecticides (OPs) that covalently inactivate serine hydrolases. KIAA1363 is one of the most abundant serine hydrolases in mouse brain. Although the physiological consequences related to the inhibition of KIAA1363 due to environmental exposures to...

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Bibliografiske detaljer
Udgivet i:Arch Biochem Biophys
Main Authors: Ross, Matthew K., Pluta, Kim, Bittles, Victoria, Borazjani, Abdolsamad, Crow, J. Allen
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727981/
https://ncbi.nlm.nih.gov/pubmed/26617293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.11.034
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