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Interaction of the Serine Hydrolase KIAA1363 with Organophosphorus Agents: Evaluation of Potency and Kinetics

Oxons are bioactive metabolites of organophosphorus insecticides (OPs) that covalently inactivate serine hydrolases. KIAA1363 is one of the most abundant serine hydrolases in mouse brain. Although the physiological consequences related to the inhibition of KIAA1363 due to environmental exposures to...

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Pubblicato in:Arch Biochem Biophys
Autori principali: Ross, Matthew K., Pluta, Kim, Bittles, Victoria, Borazjani, Abdolsamad, Crow, J. Allen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727981/
https://ncbi.nlm.nih.gov/pubmed/26617293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.11.034
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