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Serine Hydrolase KIAA1363: Toxicological and Structural Features with Emphasis on Organophosphate Interactions

Serine hydrolase KIAA1363 is highly expressed in invasive cancer cells and is the major protein in mouse brain diethylphosphorylated by and hydrolyzing low levels of chlorpyrifos oxon (CPO) (the activated metabolite of a major insecticide). It is also the primary CPO-hydrolyzing enzyme in spinal cor...

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Detalhes bibliográficos
Main Authors: Nomura, Daniel K., Durkin, Kathleen A., Chiang, Kyle P., Quistad, Gary B., Cravatt, Benjamin F., Casida, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2512971/
https://ncbi.nlm.nih.gov/pubmed/16978018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060117m
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