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Dual Roles of Brain Serine Hydrolase KIAA1363 in Ether Lipid Metabolism and Organophosphate Detoxification

Serine hydrolase KIAA1363 is an acetyl monoalkylglycerol ether (AcMAGE) hydrolase involved in tumor cell invasiveness. It is also an organophosphate (OP) insecticide-detoxifying enzyme. The key to understanding these dual properties was the use of KIAA1363 +/+ (wildtype) and −/− (gene deficient) mic...

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Détails bibliographiques
Auteurs principaux: Nomura, Daniel K., Fujioka, Kazutoshi, Issa, Roger S., Ward, Anna M., Cravatt, Benjamin F., Casida, John E.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423230/
https://ncbi.nlm.nih.gov/pubmed/18164358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.11.021
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