SPTLC1 Binds ABCA1 To Negatively Regulate Trafficking and Cholesterol Efflux Activity of the Transporter

ABCA1 transport of cholesterol and phospholipids to nascent HDL particles plays a central role in lipoprotein metabolism and macrophage cholesterol homeostasis. ABCA1 activity is regulated both at the transcriptional level and at the post-translational level. To explore mechanisms involved in the po...

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Detalhes bibliográficos
Main Authors: Tamehiro, Norimasa, Zhou, Suiping, Okuhira, Keiichiro, Benita, Yair, Brown, Cari E, Zhuang, Debbie Z, Latz, Eicke, Hornemann, Thorsten, von Eckardstein, Arnold, Xavier, Ramnik J, Freeman, Mason W, Fitzgerald, Michael L
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504083/
https://ncbi.nlm.nih.gov/pubmed/18484747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800182t
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