PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux

The absence of functional peripheral myelin protein 22 (PMP22) is associated with shortened lifespan in rodents and severe peripheral nerve myelin abnormalities in several species including humans. Schwann cells and nerves from PMP22 knock-out (KO) mice show deranged cholesterol distribution and abe...

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Udgivet i:J Neurosci
Main Authors: Zhou, Ye, Miles, Joshua R., Tavori, Hagai, Lin, Min, Khoshbouei, Habibeh, Borchelt, David R., Bazick, Hannah, Landreth, Gary E., Lee, Sooyeon, Fazio, Sergio, Notterpek, Lucia
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2019
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607759/
https://ncbi.nlm.nih.gov/pubmed/31061090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2942-18.2019
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