PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux

The absence of functional peripheral myelin protein 22 (PMP22) is associated with shortened lifespan in rodents and severe peripheral nerve myelin abnormalities in several species including humans. Schwann cells and nerves from PMP22 knock-out (KO) mice show deranged cholesterol distribution and abe...

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Publicat a:J Neurosci
Autors principals: Zhou, Ye, Miles, Joshua R., Tavori, Hagai, Lin, Min, Khoshbouei, Habibeh, Borchelt, David R., Bazick, Hannah, Landreth, Gary E., Lee, Sooyeon, Fazio, Sergio, Notterpek, Lucia
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607759/
https://ncbi.nlm.nih.gov/pubmed/31061090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2942-18.2019
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