Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22

Peripheral myelin protein 22 (PMP22) folds and trafficks inefficiently, with only 20% of newly expressed protein trafficking to the cell surface. This behavior is exacerbated in many of the mutants associated with Charcot–Marie–Tooth disease, motivating further study. Here we characterized the role...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Marinko, Justin T., Wright, Madison T., Schlebach, Jonathan P., Clowes, Katherine R., Heintzman, Darren R., Plate, Lars, Sanders, Charles R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191293/
https://ncbi.nlm.nih.gov/pubmed/33933451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100719
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items