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Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22

[Image: see text] Despite broad biochemical relevance, our understanding of the physiochemical reactions that limit the assembly and cellular trafficking of integral membrane proteins remains superficial. In this work, we report the first experimental assessment of the relationship between the confo...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Schlebach, Jonathan P., Narayan, Malathi, Alford, Catherine, Mittendorf, Kathleen F., Carter, Bruce D., Li, Jun, Sanders, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507940/
https://ncbi.nlm.nih.gov/pubmed/26102530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03743
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