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Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase

We previously demonstrated that hybrid retrotransposons composed of the yeast Ty1 element and the reverse transcriptase (RT) of HIV-1 are active in the yeast Saccharomyces cerevisiae. The RT activity of these hybrid Ty1/HIV-1 (his3AI/AIDS RT; HART) elements can be monitored by using a simple genetic...

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Bibliografski detalji
Glavni autori: Nissley, Dwight V., Boyer, Paul L., Garfinkel, David J., Hughes, Stephen H., Strathern, Jeffrey N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24958/
https://ncbi.nlm.nih.gov/pubmed/9811899
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