Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase

We have examined amino acid substitutions at residues 115 and 116 in the reverse transcriptase (RT) of HIV-1. A number of properties were examined, including polymerization and processivity on both DNA and RNA templates, strand displacement, ribonucleotide misincorporation, and resistance to nucleos...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3056
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!