Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase

We have examined amino acid substitutions at residues 115 and 116 in the reverse transcriptase (RT) of HIV-1. A number of properties were examined, including polymerization and processivity on both DNA and RNA templates, strand displacement, ribonucleotide misincorporation, and resistance to nucleos...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2000
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC16191/
https://ncbi.nlm.nih.gov/pubmed/10737786
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