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Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras

Heterologous expression systems have increased the feasibility of developing selective ligands to target nicotinic acetylcholine receptor (nAChR) subtypes. However, the α6 subunit, a component in nAChRs that mediates some of the reinforcing effects of nicotine, is not easily expressed in systems suc...

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Main Authors: Papke, Roger L., Dwoskin, Linda P., Crooks, Peter A., Zheng, Guangrong, Zhang, Zhenfa, McIntosh, J. Michael, Stokes, Clare
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494738/
https://ncbi.nlm.nih.gov/pubmed/18448138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.03.010
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