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Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras

Heterologous expression systems have increased the feasibility of developing selective ligands to target nicotinic acetylcholine receptor (nAChR) subtypes. However, the α6 subunit, a component in nAChRs that mediates some of the reinforcing effects of nicotine, is not easily expressed in systems suc...

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Detalhes bibliográficos
Main Authors: Papke, Roger L., Dwoskin, Linda P., Crooks, Peter A., Zheng, Guangrong, Zhang, Zhenfa, McIntosh, J. Michael, Stokes, Clare
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494738/
https://ncbi.nlm.nih.gov/pubmed/18448138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.03.010
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