Effect of renin inhibition and AT(1)R blockade on myocardial remodeling in the transgenic Ren2 rat

Angiotensin II (Ang II) stimulation of the Ang type 1 receptor (AT(1)R) facilitates myocardial remodeling through NADPH oxidase-mediated generation of oxidative stress. Components of the renin-angiotensin system constitute an autocrine/paracrine unit in the myocardium, including renin, which is the...

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Main Authors: Whaley-Connell, Adam, Habibi, Javad, Cooper, Shawna A., DeMarco, Vincent G., Hayden, Melvin R., Stump, Craig S., Link, Daniel, Ferrario, Carlos M., Sowers, James R.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493592/
https://ncbi.nlm.nih.gov/pubmed/18460596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00752.2007
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