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Effect of renin inhibition and AT(1)R blockade on myocardial remodeling in the transgenic Ren2 rat
Angiotensin II (Ang II) stimulation of the Ang type 1 receptor (AT(1)R) facilitates myocardial remodeling through NADPH oxidase-mediated generation of oxidative stress. Components of the renin-angiotensin system constitute an autocrine/paracrine unit in the myocardium, including renin, which is the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493592/ https://ncbi.nlm.nih.gov/pubmed/18460596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00752.2007 |
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