Salt Loading Exacerbates Diastolic Dysfunction and Cardiac Remodeling in Young Female Ren2 Rats

OBJECTIVE: Recent data would suggest pre-menopausal insulin resistant women are more prone to diastolic dysfunction than men, yet it is unclear why. We and others have reported that transgenic (mRen2)27 (Ren2) rats overexpressing the murine renin transgene are insulin resistant due to oxidative stre...

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Detalhes bibliográficos
Main Authors: Whaley-Connell, Adam T., Habibi, Javad, Aroor, Annayya, Ma, Lixin, Hayden, Melvin R., Ferrario, Carlos M., DeMarco, Vincent G., Sowers, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833978/
https://ncbi.nlm.nih.gov/pubmed/24075738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2013.08.010
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