Renin Inhibition and AT(1)R blockade improve metabolic signaling, oxidant stress and myocardial tissue remodeling

OBJECTIVE: Strategies that block angiotensin II actions on its angiotensin type 1 receptor or inhibit actions of aldosterone have been shown to reduce myocardial hypertrophy and interstitial fibrosis in states of insulin resistance. Thereby, we sought to determine if combination of direct renin inhi...

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Autors principals: Whaley-Connell, Adam, Habibi, Javad, Rehmer, Nathan, Ardhanari, Sivakumar, Hayden, Melvin R, Pulakat, Lakshmi, Krueger, Caroline, M Ferrario, Carlos, DeMarco, Vincent G, Sowers, James R
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640616/
https://ncbi.nlm.nih.gov/pubmed/23352204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.12.012
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