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Structural Basis for Ether-a-go-go-Related Gene K(+) Channel Subtype-Dependent Activation by Niflumic Acid
Niflumic acid [2-((3-(trifluoromethyl)phenyl)amino)-3-pyridin-ecarboxylic acid, NFA] is a nonsteroidal anti-inflammatory drug that also blocks or modulates the gating of a wide spectrum of ion channels. Here we investigated the mechanism of channel activation by NFA on ether-a-go-go-related gene (ER...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493422/ https://ncbi.nlm.nih.gov/pubmed/18218980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.043505 |
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