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Morphine Induces Ubiquitin-Proteasome Activity and Glutamate Transporter Degradation

Glutamate transporters play a crucial role in physiological glutamate homeostasis, neurotoxicity, and glutamatergic regulation of opioid tolerance. However, how the glutamate transporter turnover is regulated remains poorly understood. Here we show that chronic morphine exposure induced posttranscri...

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Détails bibliographiques
Auteurs principaux: Yang, Liling, Wang, Shuxing, Sung, Backil, Lim, Grewo, Mao, Jianren
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490772/
https://ncbi.nlm.nih.gov/pubmed/18539596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800809200
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