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Morphine Induces Ubiquitin-Proteasome Activity and Glutamate Transporter Degradation
Glutamate transporters play a crucial role in physiological glutamate homeostasis, neurotoxicity, and glutamatergic regulation of opioid tolerance. However, how the glutamate transporter turnover is regulated remains poorly understood. Here we show that chronic morphine exposure induced posttranscri...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490772/ https://ncbi.nlm.nih.gov/pubmed/18539596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800809200 |
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