Morphine Induces Ubiquitin-Proteasome Activity and Glutamate Transporter Degradation

Glutamate transporters play a crucial role in physiological glutamate homeostasis, neurotoxicity, and glutamatergic regulation of opioid tolerance. However, how the glutamate transporter turnover is regulated remains poorly understood. Here we show that chronic morphine exposure induced posttranscri...

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Bibliografske podrobnosti
Main Authors: Yang, Liling, Wang, Shuxing, Sung, Backil, Lim, Grewo, Mao, Jianren
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Molecular Basis of Cell and Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490772/
https://ncbi.nlm.nih.gov/pubmed/18539596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800809200
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