Morphine Induces Ubiquitin-Proteasome Activity and Glutamate Transporter Degradation

Glutamate transporters play a crucial role in physiological glutamate homeostasis, neurotoxicity, and glutamatergic regulation of opioid tolerance. However, how the glutamate transporter turnover is regulated remains poorly understood. Here we show that chronic morphine exposure induced posttranscri...

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Bibliografiska uppgifter
Huvudupphovsmän: Yang, Liling, Wang, Shuxing, Sung, Backil, Lim, Grewo, Mao, Jianren
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Molecular Basis of Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490772/
https://ncbi.nlm.nih.gov/pubmed/18539596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800809200
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