Inhibition of the Ubiquitin-Proteasome Activity Prevents Glutamate Transporter Degradation and Morphine Tolerance

Glutamate transporters play a crucial role in physiological glutamate homeostasis and neurotoxicity. Recently, we have shown that downregulation of glutamate transporters after chronic morphine exposure contributed to the development of morphine tolerance. In the present study, we examined whether r...

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Bibliografiset tiedot
Päätekijät: Yang, Liling, Wang, Shuxing, Lim, Grewo, Sung, Backil, Zeng, Qing, Mao, Jianren
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454498/
https://ncbi.nlm.nih.gov/pubmed/18986766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.09.028
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