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Inhibition of the Ubiquitin-Proteasome Activity Prevents Glutamate Transporter Degradation and Morphine Tolerance

Glutamate transporters play a crucial role in physiological glutamate homeostasis and neurotoxicity. Recently, we have shown that downregulation of glutamate transporters after chronic morphine exposure contributed to the development of morphine tolerance. In the present study, we examined whether r...

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Main Authors: Yang, Liling, Wang, Shuxing, Lim, Grewo, Sung, Backil, Zeng, Qing, Mao, Jianren
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454498/
https://ncbi.nlm.nih.gov/pubmed/18986766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.09.028
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