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Morphine Induces Ubiquitin-Proteasome Activity and Glutamate Transporter Degradation

Glutamate transporters play a crucial role in physiological glutamate homeostasis, neurotoxicity, and glutamatergic regulation of opioid tolerance. However, how the glutamate transporter turnover is regulated remains poorly understood. Here we show that chronic morphine exposure induced posttranscri...

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Detalhes bibliográficos
Main Authors: Yang, Liling, Wang, Shuxing, Sung, Backil, Lim, Grewo, Mao, Jianren
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490772/
https://ncbi.nlm.nih.gov/pubmed/18539596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800809200
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