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Neuronal Apoptosis Associated with Morphine Tolerance: Evidence for an Opioid-Induced Neurotoxic Mechanism
Tolerance to the analgesic effect of an opioid is a pharmacological phenomenon that occurs after its prolonged administration. Activation of the NMDA receptor (NMDAR) has been implicated in the cellular mechanisms of opioid tolerance. However, activation of NMDARs can lead to neurotoxicity under man...
Gorde:
| Argitaratua izan da: | J Neurosci |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Society for Neuroscience
2002
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6757968/ https://ncbi.nlm.nih.gov/pubmed/12196588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-17-07650.2002 |
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