v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: Multiple interference with the isoprenoid pathway
The isoprenoid pathway in FRTL-5 thyroid cells was found to be deeply altered on transformation with v-K-ras. A dramatic overall reduction of protein prenylation was found in v-K-ras-transformed cells in comparison with the parent FRTL-5 cells, as shown by labeling cells with [(3)H]mevalonic acid. T...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13646 |
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