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v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: Multiple interference with the isoprenoid pathway
The isoprenoid pathway in FRTL-5 thyroid cells was found to be deeply altered on transformation with v-K-ras. A dramatic overall reduction of protein prenylation was found in v-K-ras-transformed cells in comparison with the parent FRTL-5 cells, as shown by labeling cells with [(3)H]mevalonic acid. T...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24873/ https://ncbi.nlm.nih.gov/pubmed/9811854 |
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