Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.
Ras proteins are post-translationally modified by farnesylation. In the present investigation, we identified an activity in crude soluble extracts of yeast cells that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to yeast RAS2 protein. RAS2 proteins having a C-terminal Cys-...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2124698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9665 |
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