Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.

Ras proteins are post-translationally modified by farnesylation. In the present investigation, we identified an activity in crude soluble extracts of yeast cells that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to yeast RAS2 protein. RAS2 proteins having a C-terminal Cys-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Goodman, L E, Judd, S R, Farnsworth, C C, Powers, S, Gelb, M H, Glomset, J A, Tamanoi, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2124698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9665
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