Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.

Ras proteins are post-translationally modified by farnesylation. In the present investigation, we identified an activity in crude soluble extracts of yeast cells that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to yeast RAS2 protein. RAS2 proteins having a C-terminal Cys-...

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Bibliographische Detailangaben
Hauptverfasser: Goodman, L E, Judd, S R, Farnsworth, C C, Powers, S, Gelb, M H, Glomset, J A, Tamanoi, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55233/
https://ncbi.nlm.nih.gov/pubmed/2124698
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