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H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

Fatal human respiratory disease associated with the 1918 pandemic influenza virus and potentially pandemic H5N1 viruses is characterized by severe lung pathology, including pulmonary edema and extensive inflammatory infiltrate. Here, we quantified the cellular immune response to infection in the mou...

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Detalhes bibliográficos
Main Authors: Perrone, Lucy A., Plowden, Julie K., García-Sastre, Adolfo, Katz, Jacqueline M., Tumpey, Terrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483250/
https://ncbi.nlm.nih.gov/pubmed/18670648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000115
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