Intranasal Vaccination with 1918 Influenza Virus-Like Particles Protects Mice and Ferrets from Lethal 1918 and H5N1 Influenza Virus Challenge

Influenza vaccines capable of inducing cross-reactive or heterotypic immunity could be an important first line of prevention against a novel subtype virus. Influenza virus-like particles (VLPs) displaying functional viral proteins are effective vaccines against replication-competent homologous virus...

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Detalhes bibliográficos
Main Authors: Perrone, Lucy A., Ahmad, Attiya, Veguilla, Vic, Lu, Xiuhua, Smith, Gale, Katz, Jacqueline M., Pushko, Peter, Tumpey, Terrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681940/
https://ncbi.nlm.nih.gov/pubmed/19321609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00207-09
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