A90V TDP-43 Variant Results in the Aberrant Localization of TDP-43 In Vitro

TAR DNA-binding protein-43 (TDP-43) is a highly conserved, ubiquitously expressed nuclear protein that was recently identified as the disease protein in frontotemporal lobar degeneration with ubiquitin positive inclusions (FTLD-U) and amyotrophic lateral sclerosis (ALS). Pathogenic TDP-43 gene (TARD...

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Autores principales: Winton, Matthew J., Van Deerlin, Vivianna M., Kwong, Linda K., Yuan, Wuxing, Wood, Elisabeth McCarty, Yu, Chang-En, Schellenberg, Gerard D., Rademakers, Rosa, Caselli, Richard, Karydas, Anna, Trojanowski, John Q., Miller, Bruce L., Lee, Virginia M.-Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478749/
https://ncbi.nlm.nih.gov/pubmed/18505686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.05.024
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