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TDP-43 skeins show properties of amyloid in a subset of ALS cases
Aggregation of TDP-43 proteins to form intracellular inclusions is the primary pathology in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with TDP-43 inclusions (FTLD-TDP). Histologically, in the cerebral cortex and limbic regions of affected ALS and FTLD-TDP patie...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536927/ https://ncbi.nlm.nih.gov/pubmed/23124365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1055-8 |
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