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JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by which starvation induces autophagy are not completely understood. In mammalian cells, the anti-apoptotic protein, Bcl-2, binds to Beclin 1 during non-starvation conditions,...

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Bibliografiske detaljer
Main Authors: Wei, Yongjie, Pattingre, Sophie, Sinha, Sangita, Bassik, Michael, Levine, Beth
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478643/
https://ncbi.nlm.nih.gov/pubmed/18570871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.001
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