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JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by which starvation induces autophagy are not completely understood. In mammalian cells, the anti-apoptotic protein, Bcl-2, binds to Beclin 1 during non-starvation conditions,...

詳細記述

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書誌詳細
主要な著者: Wei, Yongjie, Pattingre, Sophie, Sinha, Sangita, Bassik, Michael, Levine, Beth
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478643/
https://ncbi.nlm.nih.gov/pubmed/18570871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.001
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