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JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by which starvation induces autophagy are not completely understood. In mammalian cells, the anti-apoptotic protein, Bcl-2, binds to Beclin 1 during non-starvation conditions,...

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Bibliografiska uppgifter
Huvudupphovsmän: Wei, Yongjie, Pattingre, Sophie, Sinha, Sangita, Bassik, Michael, Levine, Beth
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478643/
https://ncbi.nlm.nih.gov/pubmed/18570871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.001
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