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JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by which starvation induces autophagy are not completely understood. In mammalian cells, the anti-apoptotic protein, Bcl-2, binds to Beclin 1 during non-starvation conditions,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2478643/ https://ncbi.nlm.nih.gov/pubmed/18570871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.001 |
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