Genetic basis of attenuation of the Sabin type 3 oral poliovirus vaccine.

The poliovirus type 3 Sabin oral poliovirus vaccine strain P3/Leon/12a1b differs in nucleotide sequence from its neurovirulent progenitor P3/Leon/37 by just 10 point mutations. The contribution of each mutation to the attenuation phenotype of the vaccine strain was determined by the construction of...

Celý popis

Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Westrop, G D, Wareham, K A, Evans, D M, Dunn, G, Minor, P D, Magrath, D I, Taffs, F, Marsden, S, Skinner, M A, Schild, G C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.3.1338-1344.1989
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!