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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

IL-17-producing T helper cells (Th17) have been recently identified as a previously undescribed subset of helper T cells. Here, we demonstrate that aryl hydrocarbon receptor (Ahr) has an important regulatory function in the commitment of Th17 cells. Ahr was robustly induced under Th17-polarizing con...

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Auteurs principaux: Kimura, Akihiro, Naka, Tetsuji, Nohara, Keiko, Fujii-Kuriyama, Yoshiaki, Kishimoto, Tadamitsu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474493/
https://ncbi.nlm.nih.gov/pubmed/18607004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804231105
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