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Joint disease caused by defective gp130-mediated STAT signaling

IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling is mediated exclusively by the common signal-transducing component gp130, which is also essential for signal transduction of other cyt...

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Detalhes bibliográficos
Main Authors: Naka, Tetsuji, Kishimoto, Tadamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128925/
https://ncbi.nlm.nih.gov/pubmed/12010564
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