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Joint disease caused by defective gp130-mediated STAT signaling

IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling is mediated exclusively by the common signal-transducing component gp130, which is also essential for signal transduction of other cyt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Naka, Tetsuji, Kishimoto, Tadamitsu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128925/
https://ncbi.nlm.nih.gov/pubmed/12010564
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