Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis

The contributions of aryl hydrocarbon receptor (Ahr) to the pathogenesis of rheumatoid arthritis have not been elucidated. Here, we show that Ahr deficiency ameliorated collagen-induced arthritis, a mouse model of RA. Collagen-immunized Ahr KO mice showed decreased serum levels of such proinflammato...

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Main Authors: Nakahama, Taisuke, Kimura, Akihiro, Nguyen, Nam Trung, Chinen, Ichino, Hanieh, Hamza, Nohara, Keiko, Fujii-Kuriyama, Yoshiaki, Kishimoto, Tadamitsu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161527/
https://ncbi.nlm.nih.gov/pubmed/21825138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111786108
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