Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17–producing T-helper cell differentiation

Aryl hydrocarbon receptor (AHR) plays critical roles in various autoimmune diseases such as multiple sclerosis by controlling interleukin-17 (IL-17)–producing T-helper (T(H)17) and regulatory T cells. Although various transcription factors and cytokines have been identified as key participants in T(...

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Autors principals: Nakahama, Taisuke, Hanieh, Hamza, Nguyen, Nam Trung, Chinen, Ichino, Ripley, Barry, Millrine, David, Lee, Soyoung, Nyati, Kishan Kumar, Dubey, Praveen Kumar, Chowdhury, Kamal, Kawahara, Yukio, Kishimoto, Tadamitsu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718186/
https://ncbi.nlm.nih.gov/pubmed/23818645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311087110
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