Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C

Ítems similars

• Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis
  per: Walter, Jochen, et al.
  Publicat: (1999)
• The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.
  per: Walter, J., et al.
  Publicat: (1996)
• Separation of presenilin function in amyloid β-peptide generation and endoproteolysis of Notch
  per: Kulic, Luka, et al.
  Publicat: (2000)
• Presenilin-dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
  per: Sastre, Magdalena, et al.
  Publicat: (2001)
• The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue
  per: Tomita, Taisuke, et al.
  Publicat: (1997)