TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21(Cip1 )or Rb status

BACKGROUND: TGFβ has pleiotropic effects that range from regulation of proliferation and apoptosis to morphological changes and epithelial-mesenchymal transition (EMT). Some evidence suggests that these effects may be interconnected. We have recently reported that P53, P21(Cip1 )and pRB, three criti...

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Detaylı Bibliyografya
Asıl Yazarlar: Sheahan, Sharon, Bellamy, Christopher O, Harland, Stephen N, Harrison, David J, Prost, Sandrine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2467431/
https://ncbi.nlm.nih.gov/pubmed/18611248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-191
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