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Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21(WAF1/CIP1) activation
Mitomycin C (MC), a commonly used anticancer drug, induces DNA damage via DNA alkylation. Decarbamoyl mitomycin C (DMC), another mitomycin lacking the carbamate at C10, generates similar lesions as MC. Interstrand cross-links (ICLs) are believed to be the lesions primarily responsible for the cytoto...
Gorde:
| Argitaratua izan da: | Int J Oncol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
D.A. Spandidos
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063421/ https://ncbi.nlm.nih.gov/pubmed/27666201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3703 |
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