Loading...
Deficiency of G1 regulators P53, P21(Cip1 )and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest
BACKGROUND: TGFβ is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity. The retinoblastoma protein pRb is a key controller of E2F activity and G1/S transition which can be inhibited in viral hepatiti...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2007
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206047/ https://ncbi.nlm.nih.gov/pubmed/18021445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-215 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|