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Treating cancer when pRb and p53 cannot be reactivated

Activation of oncoproteins and inactivation of tumor suppressors induces tumorigenesis. When these events happen upstream of pRb and p53, cancer therapies may initially succeed and then fail when pRb and p53 are activated and then re-inactivated. Therapies might succeed if they remain effective when...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteur principal: Zhu, Liang
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905341/
https://ncbi.nlm.nih.gov/pubmed/27308498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1004954
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