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Treating cancer when pRb and p53 cannot be reactivated

Activation of oncoproteins and inactivation of tumor suppressors induces tumorigenesis. When these events happen upstream of pRb and p53, cancer therapies may initially succeed and then fail when pRb and p53 are activated and then re-inactivated. Therapies might succeed if they remain effective when...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Hovedforfatter: Zhu, Liang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905341/
https://ncbi.nlm.nih.gov/pubmed/27308498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1004954
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